MHC Class I (monomorphic) Mouse Monoclonal Antibody [Clone ID: CVS22]

CAT#: SM504F

MHC Class I (monomorphic) mouse monoclonal antibody, clone CVS22, FITC, Purified

Product Images

Staining of equine peripheral blood lymphocytes with MHC Class I antibody Cat.-No.SM504F.

Specifications

Product Data

• Clone Name: CVS22
• Applications: FC
• Recommended Dilution: Flow cytometry: Neat-1/10, use 10µl of this working dilution to label 10e6 cells in 100µl.
• Reactivities: Equine
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Equine leucocytes
• Specificity: All tissues
• Formulation: PBS containing 0.09% Sodium azide and 1% BSA
  Label: FITC
  State: Purified
  State: Liquid purified IgG
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: 0.1 mg/ml
• Purification: Affinity chromatography on Protein G
• Conjugation: FITC
• Background: MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.
• Synonyms: MHC Class 1, HLA Class 1