MHC Class I (monomorphic) Mouse Monoclonal Antibody [Clone ID: CVS22]

CAT#: SM504R

MHC Class I (monomorphic) mouse monoclonal antibody, clone CVS22, PE, Purified

Product Images

Staining of equine peripheral blood lymphocytes withMHC Class I anibody Cat.-No. SM504R.

Specifications

Product Data

• Clone Name: CVS22
• Applications: FC
• Recommended Dilution: Flow cytometry: Neat, use 10µl to label 10e6 cells in 100µl.
• Reactivities: Equine
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Equine leucocytes
• Specificity: All tissues
• Formulation: PBS containing 0.09% Sodium azide, 1% BSA and 5% Sucrose
  Label: PE
  State: Purified
  State: Lyophilised purified IgG
  Label: R. Phycoerythrin
• Reconstitution Method: Restore with 1.0 ml distilled water
• Purification: Affinity chromatography on Protein A
• Conjugation: PE
• Background: MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.
• Synonyms: MHC Class 1, HLA Class 1