CD45 / LCA (CD45RA) Mouse Monoclonal Antibody [Clone ID: MIL13]

CAT#: SM563F

CD45 / LCA (CD45RA) mouse monoclonal antibody, clone MIL13, FITC

Specifications

Product Data

• Clone Name: MIL13
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of neat antibody to label 10⁶ cells in 100 µl.
• Reactivities: Porcine
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Cells isolated from Porcine mesenteric lymph node.
• Specificity: This antibody recognizes the Porcine CD45RA cell surface antigen.
• Formulation: PBS
  Label: FITC
  State: Liquid purified IgG fraction
  Stabilizer: 1.0% BSA
  Preservative: 0.09% Sodium Azide
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: 0.1 mg/ml
• Conjugation: FITC
• Background: CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated.
  The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1.
  CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues.
  It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions.
  Antibodies recognising a common epitope on all of the isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc.
• Synonyms: PTPRC, Leukocyte common antigen, L-CA, T200