CD4 Mouse Monoclonal Antibody [Clone ID: KEN-4]
Specifications
Product Data | |
Clone Name | KEN-4 |
Applications | FC |
Recommended Dilution | Flow Cytometry: Use 10 µl of neat antibody to label 1x106 cells in 100 µl. |
Reactivities | Rabbit |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Rabbit thymocytes. Spleen cells from immunised mice were fused with cells of the mouse PAI myeloma cell line. |
Specificity | This antibody recognises the CD4 cell surface antigen, a 50kD glycoprotein expressed by helper T lymphocytes. |
Formulation | PBS, pH 7.4 Label: FITC State: Liquid purified Ig fraction Stabilizer: 1% BSA Preservative: 0.09% Sodium Azide Label: Fluorescein Isothiocyanate Isomer 1 |
Concentration | 0.1 mg/ml |
Purification | Affinity Chromatography on Protein G |
Conjugation | FITC |
Gene Name | - |
Database Link | |
Background | CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase. |
Synonyms | T-cell surface antigen T4/Leu-3 |
Reference Data |
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