Integrin alpha 6 (ITGA6) Mouse Monoclonal Antibody [Clone ID: Mab-5A]

CAT#: SM804F

Integrin alpha 6 (ITGA6) mouse monoclonal antibody, clone Mab-5A, FITC, Purified

USD 415.00

5 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name Mab-5A
Applications FC
Recommended Dilution Flow Cytometry.
Reactivities Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Rat oesophageal carcinoma cell line B2T.
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Specificity This CD49f antibody, clone Mab-5A recognizes Rat CD49f, also known as Integrin alpha-6, VLA-6 or CD49 antigen-like family member F. CD49f is a 1130 amino acid ~130 kDa single pass type 1 transmembrane glycoprotein which functions as a receptor for laminin when in association with either beta-1 or beta-4 integrins on platelets and epithelial cells respectively.
Clone Mab-5A does not react with Rat fibroblasts.
Formulation PBS
Label: FITC
State: Purified
State: Liquid purified IgG fraction
Stabilizer: 1% BSA
Preservative: 0.09% Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation FITC
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name integrin subunit alpha 6
Background CD49f is a 120 kD integrin family member, also known as VLA-6 alpha chain and alpha6 integrin subunit. CD49f associates with either integrin beta1 (CD29) or integrin beta4 (CD104) to form receptors (VLA-6 or alpha6 beta4 complex) for laminin and kalinin. CD49f is expressed on platelets, monocytes, T cells, placental trophoblasts, epithelial and endothelial cells. CD49f is involved in adhesion and can act as a co-stimulatory molecule for T cell activation and proliferation.
Synonyms Integrin alpha-6, VLA-6, VLA6
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.