DNA PKcs (PRKDC) Rabbit Polyclonal Antibody

CAT#: SP1136

DNA PKcs (PRKDC) rabbit polyclonal antibody, Serum


USD 610.00

5 Days*

Size
    • 100 ul

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Specifications

Product Data
Applications EMSA, IP, WB
Recommended Dilution Western Blot: 1/2000.
Immunoprecipitation.
Gel Super Shift Assays.
Immunohistochemistry on paraffin sections: 1:100; this product requires heat mediated treatment of paraffin sections; we recommend the use of antigen unmasking fluid for this purpose; a two hour incubation with SP1136 is recommended.
Reactivities Hamster, Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Human DNA-PKcs fragment
Specificity This antibody has a strong reactivity with DNA-PKcs.
Formulation State: Serum
State: Liquid serum containing 0.09% Sodium Azide
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background DNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine/threonine protein kinase whose activity is greatly stimulated by its recruitment to DNA breaks by the Ku heterodimer.
Synonyms DNPK1, p460, HYRC, HYRC1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.