CD8A Rabbit Monoclonal Antibody [Clone ID: EP1150Y]

CAT#: TA300779

Rabbit Monoclonal Antibody against CD8A (Clone EP1150Y)

Product Images

Western blot - CD8 antibody [EP1150Y]; Anti-CD8 antibody [EP1150Y] at 1/1000 dilution + THP-1 lysate at 10 ug.Predicted band size : 26 kDa.

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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD8 antibody [EP1150Y]; Human tonsil with TA300779 at 1/250 dilution.

Specifications

Product Data

• Clone Name: EP1150Y
• Applications: IHC, WB
• Recommended Dilution: WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; ICC: 1:50 - 1:100
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to residues near the C-terminus of human CD8 was used as an immunogen
• Formulation: PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• Purification: Tissue culture supernatant
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CD8a molecule
• Database Link:
  NP_741969
  Entrez Gene 925 Human
  UniProt ID P01732
• Background: The T cell coreceptor CD8 is a cell-surface glycoprotein expressed either as a disulfide-linked homodimer of two CD8alpha monomers, or a heterodimer of CD8alpha and CD8beta. These receptors interact with ligands, such as major histocompatibility complex (MHC) class I, on the outside of the cell, with proteins inside the cell, such as the tyrosine kinase p56lck, and possibly with proteins on the same cell-surface (1). CD8 plays an important role in T cell development in the thymus and T cell activation in the periphery (2).
• Synonyms: CD8; Leu2; MAL; p32
• Note: Is unsuitable for Flow Cyt or IP.

Reference Data

• Protein Families: Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
• Protein Pathways: Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway