PRA1 (RABAC1) Rabbit Monoclonal Antibody [Clone ID: EPR1747Y]

CAT#: TA301019

Rabbit Monoclonal Antibody against RABAC1 (Clone EPR1747Y)

Product Images

Western blot - PRA1 antibody [EPR1747Y] - Carboxyterminal end; Anti-PRA1 antibody [EPR1747Y] - Carboxyterminal end at 1/2000 dilution + 293 cell lysate at 10 ug.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 21 kDa.Observed band size : 21 kDa.

Specifications

Product Data

• Clone Name: EPR1747Y
• Applications: WB
• Recommended Dilution: WB: 1:1000 - 1:20000; IP: 1:30; FC: 1:100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to residues near the C-terminus of human PRA1 was used as an immunogen.
• Formulation: PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• Purification: Tissue culture supernatant
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 21 kDa
• Gene Name: Rab acceptor 1
• Database Link:
  NP_006414
  Entrez Gene 14470 MouseEntrez Gene 83583 RatEntrez Gene 10567 Human
  UniProt ID Q9UI14
• Background: PRA1 (prenylated Rab acceptor) is a general regulator of Rab proteins. It has been shown that PRA1 interacts with Rab proteins and with VAMP2. Therefore PRA1 is probably an important factor for membrane traffic, linking together the function of Rab proteins and SNAREs (1). Human cells contain more than 60 small G proteins of the Rab family, which are localized to the surfaces of distinct membrane compartments and regulate transport vesicle formation, motility, docking and fusion. Prenylated Rabs also occur in the cytosol bound to GDI (guanine nucleotide dissociation inhibitor), which binds to Rabs in their inactive state (2).
• Synonyms: PRA1; PRAF1; YIP3
• Note: Is unsuitable for ICC or IHC-P.

Reference Data

• Protein Families: Transmembrane