CD5 Rabbit Monoclonal Antibody [Clone ID: EP2952]

CAT#: TA301354

Rabbit Monoclonal Antibody against CD5 (Clone EP2952)

Product Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD5 antibody [EP2952]; Immunohistochemical analysis of paraffin-embedded human tonsil tissue using TA301354 at 1/250 dilution.

• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD5 antibody [EP2952] (TA301354); TA301354 showing positive staining in Normal spleen tissue.

• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD5 antibody [EP2952] (TA301354); TA301354 showing negative staining in Normal brain tissue.

• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD5 antibody [EP2952] (TA301354); TA301354 showing positive staining in Normal colon lymphocytes tissue.

• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD5 antibody [EP2952] (TA301354); TA301354 showing negative staining in Normal kidney tissue.

• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD5 antibody [EP2952] (TA301354); TA301354 showing negative staining in Skeletal muscle tissue.

• Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD5 antibody [EP2952] (TA301354); TA301354 showing negative staining in Normal brain tissue.

• Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD5 antibody [EP2952] (TA301354); TA301354 showing positive staining in Normal spleen tissue.

• Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD5 antibody [EP2952] (TA301354); TA301354 showing negative staining in Normal colon tissue.

• Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD5 antibody [EP2952] (TA301354); TA301354 showing negative staining in Normal kidney tissue.

• Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD5 antibody [EP2952] (TA301354); TA301354 showing negative staining in Skeletal muscle tissue.

• Other-Anti-CD5 antibody [EP2952] (TA301354); Equilibrium disassociation constant (KD).

Show all 12 images

Specifications

Product Data

• Clone Name: EP2952
• Applications: Assay, IHC
• Recommended Dilution: WB: 1: 10,000~50,000; IHC: 1:250~500; ICC: 1: 100~250; IP: 1:50
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to residues in human CD5 was used as an immunogen.
• Formulation: PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• Purification: Tissue culture supernatant
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 55 kDa
• Gene Name: CD5 molecule
• Database Link:
  NP_055022
  Entrez Gene 12507 MouseEntrez Gene 921 Human
  UniProt ID P06127
• Background: CD5 (Lymphocyte antigen T1/Leu-1) is a transmembrane glycoprotein which has been implicated as a receptor in the regulation of T-cell proliferation (1). CD5 is part of the scavenger receptor cysteine-rich (SRCR) family group B and it is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by T cell leukemia, lymphomas, and activated T cells. Occasionally, CD5 antigen is also expressed on a subset of B cells. Mantle cell lymphomas (same as diffuse centrocytic lymphomas) are CD5+ while the follicle center cell lymphomas are CD5. A ligand for CD72/LYB-2, CD5 has been linked to negative regulation of T cell and B cell receptors signaling (2).
• Synonyms: LEU1; T1
• Note: Does not react with Mouse, Rat

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Hematopoietic cell lineage