Prostaglandin dehydrogenase 1 (HPGD) Rabbit Polyclonal Antibody

CAT#: TA301413

Rabbit Polyclonal Antibody against 15-PGDH

Product Images

Immunocytochemistry/Immunofluorescence: 15-PGDH/HPGD Antibody TA301413 - 15-PGDH antibody was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

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  Simple Western: 15-PGDH/HPGD Antibody TA301413 - Simple Western lane view shows a specific band for 15-PGDH/HPGD in 0.5 mg/ml of Lovo (left) and HeLa (right) lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.

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  Western Blot: 15-PGDH/HPGD Antibody TA301413 - Western blot analysis of 15-PGDH in Lovo cell lysate.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry: 1:200, Immunocytochemistry/ Immunofluorescence, Western Blot: 1:5000-1:6000, Immunohistochemistry-Paraffin: 1:200, Immunohistochemistry-Frozen, Simple Western: 1:500, Knockdown Validated
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Purified type I human placental 15-PGDH protein.
• Formulation: Tris-glycine, 150mM NaCl and 0.05% sodium azide
• Purification: protein A purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: hydroxyprostaglandin dehydrogenase 15-(NAD)
• Database Link:
  NP_000851
  Entrez Gene 3248 Human
  UniProt ID P15428
• Background: 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is a novel tumor suppressor in the COX-2 pathway. The protein is found in many normal tissues and appears to be down-regulated in colorectal and lung carcinoma tissue.
• Synonyms: 15-PGDH; PGDH; PGDH1; PHOAR1; SDR36C1

Reference Data

• Protein Families: Druggable Genome