HSD3B1 Mouse Monoclonal Antibody [Clone ID: FDO66Q]

CAT#: TA301417

Mouse Monoclonal Antibody against HSD3B1 (FDO66Q) - Trophoblast Marker

Product Images

Immunohistochemistry: HSD3B1 Antibody (FDO66Q) TA301417 - Staining of placental villi.

Specifications

Product Data

• Clone Name: FDO66Q
• Applications: IHC
• Recommended Dilution: Western Blot, Immunohistochemistry-Paraffin: 10-20 ug/ml, Immunohistochemistry: 10-20 ug/ml, Immunocytochemistry/ Immunofluorescence: 10-20 ug/ml, Immunohistochemistry-Frozen: 10-20 ug/ml
• Reactivities: Human, Baboon, Marmoset
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: JEG Choriocarcinoma cells
• Formulation: Tris-glycine, 150mM NaCl and 0.05% sodium azide
• Concentration: lot specific
• Purification: protein G purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
• Database Link:
  NP_000853
  Entrez Gene 3283 Human
  UniProt ID P14060
• Background: 3-beta hydroxysteroid dehydrogenase (HSD3B1) is a bifunctional enzyme involved in the oxidative conversion of ketosteroids that plays an important role in the synthesis of all steroid hormones. There are two HSD3B1 proteins, designated type I and type II, that are expressed by different genes and function in different areas of the body. HSD3B1 has also been shown to be a highly specific and sensitive trophoblast-associated marker (Mao et. al).
• Synonyms: 3BETAHSD; HSD3B; HSDB3; HSDB3A; I; SDR11E1

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Androgen and estrogen metabolism, C21-Steroid hormone metabolism, Metabolic pathways