FE65 (APBB1) Rabbit Polyclonal Antibody

CAT#: TA301423

Rabbit Polyclonal Antibody against Fe65

Product Images

Western Blot: FE65 Antibody TA301423 - Protein on HEK 293 cell lysate.

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  Western Blot: FE65 Antibody TA301423 - Cells were transfected with the pCMV6-ENTRY control or pCMV6-ENTRY APBB1 cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-APBB1.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Immunoprecipitation: 2-10 ug, Western Blot: 1:1000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant rat protein expressed in bacteria.
• Formulation: PBS, 15% glycerol and 0.02% sodium azide
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: amyloid beta precursor protein binding family B member 1
• Database Link:
  NP_001155
  Entrez Gene 11785 MouseEntrez Gene 29722 RatEntrez Gene 322 Human
  UniProt ID O00213
• Background: FE65 is a signaling adaptor of APP protein. The FE65/APP complex was shown to translocate into the cell nucleus and regulate gene expression. Genetic studies in mice validated FE65-APP interaction and molecular studies provided evidence on the role of the complex in abnormal signaling detected in brains of Alzheimer Disease patients.
• Synonyms: FE65; MGC:9072; RIR

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: Alzheimer's disease