HIF 2 alpha (EPAS1) Mouse Monoclonal Antibody [Clone ID: EP190B]

CAT#: TA301435

Mouse Monoclonal Antibody against HIF-2 alpha (ep190b)


USD 479.00

3 Weeks*

Size
    • 100 ul

Product Images

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Specifications

Product Data
Clone Name EP190B
Applications IHC, WB
Recommended Dilution Chromatin Immunoprecipitation (ChIP), Gel Supershift Assay, Gel Super Shift Assays, Immunohistochemistry-Frozen, In vivo assay, Knockdown Validated, Western Blot: 1 - 2 ug/mL, Immunohistochemistry: 1:150 - 1:300, Immunohistochemistry-Paraffin: 1:150 - 1:300, Simple Western: 1:100, Flow Cytometry: 1:400, ELISA: 1:100-1:2000, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation
Reactivities Human, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human HIF-2 alpha amino acids 535-631.
Formulation PBS and 0.1% sodium azide
Purification protein G purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name endothelial PAS domain protein 1
Background Hypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. HIF-2 alpha is predominantly expressed in highly vascularized tissues of adult humans and endothelial cells of the embryonic and adult mouse, whereas HIF-1 alpha functions primarily in extravascular tissues. HIF-2 alpha is also a potent activator of the tie-2 gene, which is known to be selectively expressed in endothelial cells.
Synonyms bHLHe73; ECYT4; HIF2A; HLF; MOP2; PASD2
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Pathways in cancer, Renal cell carcinoma

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.