HSP27 (HSPB1) Rabbit Polyclonal Antibody
Frequently bought together (3)
Recombinant protein of human heat shock 27kDa protein 1 (HSPB1)
USD 823.00
Other products for "HSP27"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western Blot: 0.5-1.0 ug/ml, Immunocytochemistry/ Immunofluorescence: 1:50 - 1:150 |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthetic peptide made to an internal region of the human Crystallin AB protein (within residues 100-175). [Swiss-Prot P02511] |
Formulation | Tris-citrate/phosphate (pH 7-8) and 0.1% sodium azide |
Concentration | lot specific |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | heat shock protein family B (small) member 1 |
Database Link | |
Background | Crystallin AB (CryAB) is a developmentally regulated small heat shock protein known to protect cells from stress damage. It may also play an important role in the Golgi reorganization during cell division. CryAB is known to be associated with a number of neurodegenerative pathologies such as Alzheimer disease amd multiple sclerosis. As well, it has been found to be expressed in breast tumors of patients with shorter survival, suggesting that it may be a useful marker in identifying aggressive breast cancer. |
Synonyms | CMT2F; HEL-S-102; HMN2B; HS.76067; Hsp25; HSP27; HSP28; SRP27 |
Reference Data | |
Protein Pathways | MAPK signaling pathway, VEGF signaling pathway |
Documents
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