PDK1 Rabbit Polyclonal Antibody

CAT#: TA301454

Rabbit Polyclonal Antibody against PDK1

Product Images

Immunocytochemistry/Immunofluorescence: PDK-1 Antibody TA301454 - Antibody was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

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  Western Blot: PDK-1 Antibody TA301454 - Detection of PDK-1 in human heart lysate using NB 100-2383 at 2 ug/ml.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Immunocytochemistry/ Immunofluorescence: 1:1000-1:2000, Western Blot: 2 ug/ml
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide made to a C-Terminal portion of the human PDK1 protein sequence (between residues 350-436). [Swiss-Prot Q15118]
• Formulation: Tris-glycine, 150mM NaCl and 0.05% sodium azide
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: pyruvate dehydrogenase kinase 1
• Database Link:
  NP_002601
  Entrez Gene 5163 Human
  UniProt ID Q15118
• Background: Pyruvate dehydrogenase kinase isoform 1 (PDK1) inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
• Synonyms: isoenzyme 1; isozyme 1; mitochondrial pyruvate dehydrogenase kinase isoenzyme 1; pyruvate dehydrogenase kinase

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Fc epsilon RI signaling pathway, Neurotrophin signaling pathway, T cell receptor signaling pathway