Thimet Oligopeptidase (THOP1) Mouse Monoclonal Antibody [Clone ID: 4D6]

CAT#: TA301468

Mouse Monoclonal Antibody against Thimet Oligopeptidase (4D6)


USD 424.00

5 Days*

Size
    • 100 ul

Product Images

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Specifications

Product Data
Clone Name 4D6
Applications IHC, WB
Recommended Dilution Immunohistochemistry: 1:400, Immunocytochemistry/ Immunofluorescence: 1:10-1:500, Western Blot: 1:750-1:3000, Immunohistochemistry-Paraffin: 1:400
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen A synthetic peptide corresponding to residues 56-72 of human thimet oligopeptidase.
Formulation Tris-glycine and 150mM NaCl and 0.05% sodium azide
Concentration lot specific
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name thimet oligopeptidase 1
Background A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enxymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
Synonyms EP24.15; MEPD_HUMAN; MP78; TOP
Reference Data
Protein Families Druggable Genome, Protease
Protein Pathways Renin-angiotensin system

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.