SCARB1 Rabbit Polyclonal Antibody

CAT#: TA301489

90 /1002 Citations
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Rabbit Polyclonal Antibody against SR-BI


USD 490.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution WB: 1: 1000-1:5000
Reactivities Hamster, Human, Mink, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen A C-terminal peptide containing residues from mouse Scavenger Receptor-BI (within residues 450-509).
Formulation Tris-citrate/phosphate [pH 7-8] buffer. and 0.1% Sodium Azide
Purification Affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name scavenger receptor class B member 1
Background High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
Synonyms CD36L1; CLA-1; CLA1; HDLQTL6; SR-BI; SRB1
Reference Data
Protein Families Druggable Genome, Transmembrane

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Product Citations

Early changes in the hypothalamic region in prodromal Huntington disease revealed by MRI analysis
Soneson, Fontes, Zhou et al
Neurobiol Dis (2010) 40 (3), 531-43 DOI: 10.1016/j.nbd.2010.07.013
Evaluation of optimized b-value sampling schemas for diffusion kurtosis imaging with an application to stroke patient data
Yan, Zhou, Ying et al
Comput Med Imaging Graph (2013) 37 (4), 272-80 DOI: 10.1016/j.compmedimag.2013.04.007
Preparing for selective inhibition within frontostriatal loops
Smittenaar, Guitart-Masip, Lutti et al
J Neurosci (2013) 33 (46), 18087-97 DOI: 10.1523/JNEUROSCI.2167-13.2013
Showing 1-5 of 27 papers.
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