MAT2A Rabbit Polyclonal Antibody

CAT#: TA301494

Rabbit Polyclonal Antibody against MAT1/2 alpha

Product Images

Simple Western: MAT1/2A Antibody TA301494 - Simple Western lane view shows a specific band for MAT1/2 A in 0.5 mg/ml of HepG2 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.

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  Western Blot: MAT1/2A Antibody TA301494 - Detection of MAT2A in HepG2 whole cell lysates using TA301494.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 2 ug/ml, Simple Western: 1:10
• Reactivities: Human, Rat, Bovine, Zebrafish, Orang-Utan, Monkey (Does not react with: Mouse)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide made to an internal portion of the human MAT2A protein (within residues 100-200). [Swiss-Prot# P31153]
• Formulation: PBS, 30% glycerol and 0.1% sodium azide
• Concentration: lot specific
• Purification: peptide affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: methionine adenosyltransferase 2A
• Database Link:
  NP_005902
  Entrez Gene 171347 RatEntrez Gene 232087 MouseEntrez Gene 695362 MonkeyEntrez Gene 4144 Human
  UniProt ID P31153
• Background: MAT1A and MAT2A are catalytic subunits of methionine adenosyltransferase (MAT), which catalyzes the formation of S-adenosyltransferase for methionine catabolism. Inactivation of MAT1A has been linked to liver disease. In addition, in certain liver cancers expression of MAT1A is replaced by expression of MAT1B. Overexpression of MAT2A has also been observed in colon cancer, leading to the proposal that MAT2A facilitates cancer cell growth.
• Synonyms: MATA2; MATII; SAMS2

Reference Data

• Protein Pathways: Cysteine and methionine metabolism, Metabolic pathways, Selenoamino acid metabolism