FOXP3 Rabbit Polyclonal Antibody

CAT#: TA301515

Rabbit Polyclonal Antibody against FOXP3

Product Images

Detection of murine FOXP3. Lane 1: Human CD4+CD25+ PBL, lane 2: HEK293T transfected with human Foxp3 cDNA, lane 3: 293/mouse foxp3, lane 4: 293/empty vector

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1: 1000-5000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide made to the N-terminal region of human FOXP3 (between residues 1-50).
• Formulation: Tris-citrate/phosphate, pH 7-8, 0.1% sodium Azide
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: forkhead box P3
• Database Link:
  NP_054728
  Entrez Gene 20371 MouseEntrez Gene 50943 Human
  UniProt ID Q9BZS1
• Background: FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
• Synonyms: AIID; DIETER; IPEX; JM2; PIDX; XPID

Reference Data

• Protein Families: Transcription Factors