SIRT6 Rabbit Polyclonal Antibody

CAT#: TA301524

Rabbit Polyclonal Antibody against SIRT6

Product Images

Immunocytochemistry/Immunofluorescence: SIRT6 Antibody TA301524 - SIRT6 antibody was tested in Hela cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

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  Western Blot: SIRT6 Antibody TA301524 - Detection of SIRT6 in HeLa whole cell lysate.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Immunocytochemistry/ Immunofluorescence: 1:500, Western Blot: 2 ug/ml
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide made to a C-terminal region of the human SIRT6 protein (within residues 300-355). [Swiss-Prot Q8N6T7]
• Formulation: Tris-citrate/phosphate (pH 7-8) and 0.1% sodium azide
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: sirtuin 6
• Database Link:
  NP_057623
  Entrez Gene 51548 Human
  UniProt ID Q8N6T7
• Background: Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human ageing.
• Synonyms: SIR2L6

Reference Data

• Protein Families: Druggable Genome, Transcription Factors