HIF1AN Rabbit Polyclonal Antibody

CAT#: TA301533

Rabbit Polyclonal Antibody against Factor Inhibiting HIF-1


USD 424.00

In Stock*

Size
    • 100 ul

Product Images

Frequently bought together (3)
Recombinant protein of human hypoxia inducible factor 1, alpha subunit inhibitor (HIF1AN)
    • 20 ug

USD 823.00


Transient overexpression lysate of hypoxia inducible factor 1, alpha subunit inhibitor (HIF1AN)
    • 100 ug

USD 396.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 159.00

Other products for "HIF1AN"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution Immunohistochemistry: 1:100, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation: 1:10-1:500, Electron Microscopy, Immunohistochemistry-Paraffin: 1:50-1:200, Immunohistochemistry-Frozen: 1:50-1:200, Western Blot: 1:1000-1:5000, Knockdown Validated, Knockout Validated
Reactivities Human, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A C-terminal region synthetic peptide made to the human FIH protein sequence (between residues 300 and the C-terminus).
Formulation Tris-citrate/phosphate [pH 7-8] buffer. and 0.1% Sodium Azide
Concentration lot specific
Purification Immunogen affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name hypoxia inducible factor 1 alpha subunit inhibitor
Background Factor Inhibiting HIF1 (FIH) protein facilitates repression of HIF-1 transcriptional activity by binding to VHL, which acts as a transcriptional corepressor. VHL inhibits HIF-1 alpha transactivation function by recruiting histone deacetylases. Involvement of VHL in association with FIH provides a unifying mechanism for the modulation of HIF-1 alpha protein stabilization and transcriptional activation in response to changes in cellular oxygen concentration.
Synonyms FIH1
Reference Data
Protein Families Druggable Genome

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.