LC3B (MAP1LC3B) Rabbit Polyclonal Antibody

CAT#: TA301541

Rabbit Polyclonal Antibody against LC3


USD 512.00

2 Weeks*

Size
    • 100 ul

Frequently bought together (1)
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Specifications

Product Data
Applications IHC, WB
Recommended Dilution Immunocytochemistry/ Immunofluorescence: 1:200, Immunohistochemistry-Frozen, Simple Western: 1:50, Flow Cytometry, Proximity Ligation Assay, Knockdown Validated, SDS-Page, ELISA, Immunoprecipitation: 20 ug/500 ug of protein, Immunohistochemistry: 1:200 - 1:400, Immunohistochemistry-Paraffin: 1:200 - 1:400, Western Blot: 0.5 - 2.0 ug/mL, Chromatin Immunoprecipitation (ChIP), Immunoblotting, Knockout Validated
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic peptide made to an N-terminal portion of the human LC3 protein sequence (between residues 1-100).
Formulation PBS, 30% Glycerol and 0.1% sodium azide
Concentration lot specific
Purification Immunogen affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name microtubule associated protein 1 light chain 3 beta
Background LC3, a mammalian homologue of Apg8, was originally identified as microtubule-associated protein 1 light chain 3. It is a component of both the MAP1A and MAP1B microtubule-binding domains and the heavy-chain independent regulation of LC3 expression might modify MAP1 microtubule-binding activity during development. However, LC3 is now thought to also be involved in autophagy. LC3-I is cytosolic and LC3-II is membrane bound and enriched in the autophagic vacuole fraction. LC3-II is the first mammalian protein identified that specifically associates with the autophagosome membranes.
Synonyms 1BLC3; ATG8F; LC3B; MAP1A; MAP1LC3B-a
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.