Wilms Tumor Protein (WT1) Mouse Monoclonal Antibody [Clone ID: 6F-H2]

CAT#: TA301555

Mouse Monoclonal Antibody against Wilms Tumor 1 (6F-H2)


USD 457.00

2 Weeks*

Size
    • 100 ul

Product Images

Frequently bought together (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 159.00

Other products for "Wilms Tumor Protein"

Specifications

Product Data
Clone Name 6F-H2
Applications IHC, WB
Recommended Dilution Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Frozen: 1: 400, Immunohistochemistry-Paraffin: 1:400, Simple Western: 1:50, Western Blot: 2 ug/ml, Immunoprecipitation: 2-10 ug/ml lysate, Immunohistochemistry: 1:400
Reactivities Human
Host Mouse
Isotype IgG1, kappa
Clonality Monoclonal
Immunogen Human recombinant WT1 protein (residues 1-181). [Swiss-Prot# P19544]
Formulation Tris-glycine, 150mM NaCl and 0.05% sodium azide
Purification IgG purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name Wilms tumor 1
Background Wilms?tumor (WT) is an embryonal malignancy of the kidney that affects 1 in 10,000 infants and, like retinoblastoma, is observed in both sporadic and inherited forms. The Wilms?tumor locus has been mapped at chromosome 11p13 as a tumor suppressor gene which encodes a DNA binding protein with four zinc fingers and a glutamine-proline rich amino terminus. The Wilms?tumor protein binds the DNA sequence GCGGGGGCG, a recognition element common to the early growth response (Egr) family of Zn2+ finger transcriptional activators. However, in contrast to Egr transcription factors, WT1 behaves as a transcriptional repressor in transient transfection assays with synthetic promotor constructs.
Synonyms AWT1; EWS-WT1; GUD; NPHS4; WAGR; WIT-2; WT33
Reference Data
Protein Families Druggable Genome, Transcription Factors

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.