Macrophage Scavenger Receptor I (MSR1) Rabbit Polyclonal Antibody

CAT#: TA301566

Rabbit Polyclonal Antibody against Macrophage Scavenger Receptor

Product Images

Immunocytochemistry/Immunofluorescence: SR-AI/MSR Antibody TA301566 - Antibody was tested in Raw cells at a 1:50 dilution against Dylight 488 (Green). Alpha-tubulin and nuclei were counterstained against Dylight 550 (Red) and DAPI (Blue), respectively.

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  Western Blot: SR-AI/MSR Antibody TA301566 - Detection of MSR in human liver using TA301566.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 2 ug/mL, Immunocytochemistry/ Immunofluorescence: 1:50 - 1:200
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide made to an internal portion of the human MSR protein sequence (between residues 300-400). UniProt P21757
• Formulation: Tris-glycine and 150mM NaCl and 0.05% sodium azide
• Purification: peptide affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: macrophage scavenger receptor 1
• Database Link:
  NP_619729
  Entrez Gene 20288 MouseEntrez Gene 4481 Human
  UniProt ID P21757
• Background: Macrophage scavenger receptors (MSR) are membrane glycoproteins that mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta). While the normal role of MSR is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Abeta deposition in Alzheimer's disease (AD).
• Synonyms: CD204; phSR1; phSR2; SCARA1; SR-A; SRA

Reference Data

• Protein Families: Druggable Genome, Transmembrane