Nucleophosmin (NPM1) Rabbit Polyclonal Antibody

CAT#: TA301725

Rabbit Polyclonal Antibody against Nucleophosmin, mutant - AML Marker


USD 424.00

2 Weeks*

Size
    • 100 ul

Product Images

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Specifications

Product Data
Applications WB
Recommended Dilution Immunocytochemistry/ Immunofluorescence: 1:50 - 1:100, Immunohistochemistry: 1:50 - 1:100, Immunohistochemistry-Paraffin: 1:50 - 1:100, Flow Cytometry: 1:100, Immunoprecipitation: 1:50, Western Blot: 1:500
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic peptide made to a C-terminal region of human mutant nucleophosmin (exact sequence is within residues 250-298).
Formulation 100 mM glycine, 65 mM Tris, pH 7.0 in 50% glycerol
Purification Affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Background Nucleophosmin (NPM) is a multi-functional protein that is involved in many cellular activities including cell growth, proliferation and transformation. It is frequently overexpressed in solid tumors, and has recently been found to be mutated and aberrantly localized in the cytoplasm of leukaemic blasts in patients with acute myeloid leukemia (AML).
Synonyms B23; NPM
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.