MRE11 Rabbit Polyclonal Antibody

CAT#: TA301767

Rabbit Polyclonal Antibody against Mre11


USD 457.00

5 Days*

Size
    • 50 ul

Product Images

Frequently bought together (3)
Recombinant protein of human MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 1
    • 20 ug

USD 823.00


Transient overexpression lysate of MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 1
    • 100 ug

USD 396.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 159.00

Other products for "MRE11"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution Chromatin Immunoprecipitation (ChIP), Knockdown Validated, Proximity Ligation Assay, Immunocytochemistry/ Immunofluorescence: 1:200, Immunohistochemistry-Paraffin: 1:10 - 1:500, Immunohistochemistry: 1:10 - 1:500, Simple Western: 1:250, Western Blot: 1:5000, Immunoprecipitation: 3 uL, Flow Cytometry, Immunoblotting, Immunohistochemistry-Frozen, Knockout Validated, ELISA
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Full length human Mre11 protein
Formulation Sodium azide
Purification Affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name MRE11 homolog A, double strand break repair nuclease
Background The hMre11-hRad50-NBS1 protein plays a central role in the human cellular DNA-Damage response, with recent studies indicating that these proteins help link DNA-damage detection to DNA-repair and cell cycle-checkpoint functions. This protein complex has been implicated in the activation of cell cycle-regulatory pathways, due to the fact that the NBS1 gene mutates in the chromosomal-instability syndrome, Nijmegen breakdown syndrome (NBS), which is characterized by increased cancer incidence, cell cycle checkpoint defects, and ionizing radiation sensitivity.
Synonyms ATLD; HNGS1; MRE11; MRE11B
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Homologous recombination, Non-homologous end-joining

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.