p95 NBS1 (NBN) Rabbit Polyclonal Antibody
Frequently bought together (2)
Transient overexpression lysate of nibrin (NBN)
USD 605.00
Other products for "p95 NBS1"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Chromatin Immunoprecipitation (ChIP), In-situ Hybridization, Western Blot: 1:1000, Knockdown Validated, ELISA, Immunohistochemistry: 1:100 - 1:200, Immunohistochemistry-Paraffin: 1:100 - 1:200, SDS-Page, Immunoblotting, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/ Immunofluorescence: 1:50-1:200, Immunoprecipitation: 3 ul, Knockout Validated |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Human NBS1 protein (betwqeen residues 1-705) |
Formulation | Whole antisera and 0.02% sodium azide |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | nibrin |
Database Link | |
Background | The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions. |
Synonyms | AT-V1; AT-V2; ATV; NBS; NBS1; P95 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Homologous recombination |
Documents
Product Manuals |
FAQs |
SDS |
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