Apolipoprotein E (APOE) Rabbit Polyclonal Antibody

CAT#: TA302010

Rabbit Polyclonal Antibody against APOE (C-term)


USD 450.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 1:1000, IHC: 1:10~50
Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen This APOE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human APOE.
Formulation Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Concentration lot specific
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 36154 Da
Gene Name apolipoprotein E
Background Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III),in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Synonyms AD2; APO-E; LDLCQ5; LPG
Reference Data
Protein Families Adult stem cells, Druggable Genome, Secreted Protein, Stem cell - Pluripotency
Protein Pathways Alzheimer's disease

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.