EIF4EBP1 Rabbit Polyclonal Antibody

CAT#: TA302037

Rabbit Polyclonal Antibody against EIF4EBP1 (T69)


USD 450.00

In Stock*

Size
    • 100 ug

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 1:1000, IHC: 1:10~50
Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen This EIF4EBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from human EIF4EBP1.
Formulation Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 12449 Da
Gene Name eukaryotic translation initiation factor 4E binding protein 1
Background EIF4EBP1 is one member of a family of translation repressor proteins. It directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Synonyms 4E-BP1; 4EBP1; BP-1; PHAS-I
Reference Data
Protein Pathways Acute myeloid leukemia, ErbB signaling pathway, Insulin signaling pathway, mTOR signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.