PBK Rabbit Polyclonal Antibody

CAT#: TA302075

Rabbit Polyclonal Antibody against PBK (C-term C300)

Product Images

Western blot analysis of PBK (arrow) using rabbit polyclonal PBK Antibody (C-term C300) (Cat.#TA302075).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PBK gene (Lane 2) (Origene Technologies).

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  PBK/TOPK Antibody (Mouse C-term) (Cat. #TA302075) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PBK/TOPK antibody detected the PBK/TOPK protein (arrow).

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  Formalin-fixed and paraffin-embedded human testis tissue reacted with PBK Antibody (C-term C300) (Cat.#TA302075), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:1000, IHC: 1:10~50
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This PBK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-317 amino acids from the C-terminal region of human PBK.
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Concentration: lot specific
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 36085 Da
• Gene Name: PDZ binding kinase
• Database Link:
  NP_060962
  Entrez Gene 52033 MouseEntrez Gene 55872 Human
  UniProt ID Q96KB5
• Background: PBK is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.
• Synonyms: CT84; HEL164; Nori-3; SPK; TOPK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase