NR0B1 Rabbit Polyclonal Antibody

CAT#: TA302082

Rabbit Polyclonal Antibody against NR0B1 (N-term)

Product Images

NROB1 Antibody (N-term) (Cat. #TA302082) western blot analysis in Hela, NCI-H292, PC-3 cell line lysates (35ug/lane).This demonstrates the NROB1 antibody detected the NROB1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This DAX1 (NR0B1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-34 amino acids from the N-terminal region of human DAX1 (NR0B1).
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Concentration: lot specific
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 51718 Da
• Gene Name: nuclear receptor subfamily 0 group B member 1
• Database Link:
  NP_000466
  Entrez Gene 190 Human
  UniProt ID P51843
• Background: NROB1 contains a DNA-binding domain and acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in the gene for NROB1 result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
• Synonyms: AHC; AHCH; AHX; DAX-1; DAX1; DSS; GTD; HHG; NROB1; SRXY2

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors