WIF1 Rabbit Polyclonal Antibody

CAT#: TA302106

Rabbit Polyclonal Antibody against WIF1 (N-term)

Product Images

Western blot analysis of WIF1 (arrow) using rabbit polyclonal WIF1 Antibody (N-term) (Cat.#TA302106).

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  Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with WIF1 (Human C-term) (Cat.#TA302106), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:1000, IHC: 1:10~50
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This WIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-80 amino acids from the N-terminal region of human WIF1.
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Concentration: lot specific
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 41528 Da
• Gene Name: WNT inhibitory factor 1
• Database Link:
  NP_009122
  Entrez Gene 24117 MouseEntrez Gene 114557 RatEntrez Gene 11197 Human
  UniProt ID Q9Y5W5
• Background: WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 is a secreted protein, which binds WNT proteins and inhibits their activities. This protein contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. It may be involved in mesoderm segmentation. This protein is found to be present in fish, amphibia and mammals.
• Synonyms: WIF-1

Reference Data

• Protein Families: Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway
• Protein Pathways: Wnt signaling pathway