NUAK2 Rabbit Polyclonal Antibody

CAT#: TA302109

Rabbit Polyclonal Antibody against NUAK2 (N-term)

Product Images

Western blot analysis of NUAK2 (arrow) using rabbit polyclonal NUAK2 Antibody (N-term) ([RB08560]). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NUAK2 gene (Lane 2) (Origene Technologies).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This NUAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human NUAK2.
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 69612 Da
• Gene Name: NUAK family kinase 2
• Database Link:
  NP_112214
  Entrez Gene 81788 Human
  UniProt ID Q9H093
• Background: Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.
• Synonyms: SNARK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase