Caspase 4 (CASP4) Goat Polyclonal Antibody

CAT#: TA302442

Goat Polyclonal Antibody against CASP4


USD 375.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications WB
Recommended Dilution ELISA: 1:16,000. WB: 0.3-2µg/ml.
Reactivities Human
Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence CKERAEEIYPIKERN, from the internal region of the protein sequence according to NP_001216; NP_150649; NP_150650.
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 46888 Da
Gene Name caspase 4
Background This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq]
Synonyms ICE(rel)II; ICEREL-II; ICH-2; Mih1; TX
Reference Data
Protein Families Druggable Genome, Protease

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.