Numb Goat Polyclonal Antibody

CAT#: TA302758

Goat Polyclonal Antibody against NUMB

Product Images

TA302758 staining (0.3ug/ml) of Mouse Brain lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

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  Figure from citation: Western Blot of NUMB protein level by using anti-NUMB antibody in small intestine and liver of the mice. Dilution: 1:1000 View Citation

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:16,000. WB: 0.3-1.0 µg/ml.
• Reactivities: Human, Mouse
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-PFSSDLQKTFEIEL, from the C Terminus of the protein sequence according to NP_001005743.1; 001005744.1; NP_003735; NP_001005745.1.
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: numb homolog (Drosophila)
• Database Link:
  NP_035079
  Entrez Gene 8650 HumanEntrez Gene 480381 DogEntrez Gene 18222 Mouse
  UniProt ID Q9QZS3
• Background: The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: h-Numb; S171