PD L1 (CD274) Goat Polyclonal Antibody

CAT#: TA302988

Goat Polyclonal Antibody against PD-L1 / CD274


USD 375.00

3 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 1-3 µg/ml. IHC: 4-6 µg/ml.
Reactivities Human
Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence CKKQSDTHLEET, from the C Terminus of the protein sequence according to NP_054862.1.
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name CD274 molecule
Background Involved in the costimulatory signal, essential for T lymphocyte proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibit T-cell proliferation and cytokine production
Synonyms B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1
Note In paraffin embedded Human Placenta shows membranous staining of cytotrophoblasts
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.