CCKAR Goat Polyclonal Antibody

CAT#: TA303030

Goat Polyclonal Antibody against CCKAR

Product Images

TA303030 (10ug/ml) staining of paraffin embedded Human Pancreas. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: ELISA: 1:4,000. WB: 10µg/ml.
• Reactivities: Human, Rat
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-FEASQKKSAKERKPST, from the internal region of the protein sequence according to NP_000721.1.
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cholecystokinin A receptor
• Database Link:
  NP_000721
  Entrez Gene 24889 RatEntrez Gene 886 Human
  UniProt ID P32238
• Background: This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine. [provided by RefSeq]
• Synonyms: CCK-A; CCK1-R; CCK1R; CCKRA

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction