PIK3CD Rabbit Monoclonal Antibody [Clone ID: Y387]

CAT#: TA303639

Rabbit monoclonal antibody against PI3-kinase p110 subunit delta(Y387)

Product Images

Western blot - PI 3 Kinase p110 delta antibody [Y387]; Anti-PI 3 Kinase p110 delta antibody [Y387] at 1/500 dilution + Jurkat cell lysate.Predicted band size : 119 kDa.Observed band size : 110 kDa.

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  Immunocytochemistry/ Immunofluorescence - PI 3 Kinase p110 delta antibody [Y387]; Immunofluorescent staining of HeLa cells using TA303639 at 1/250 dilution.

Specifications

Product Data

• Clone Name: Y387
• Applications: IF, WB
• Recommended Dilution: WB: 1:500; ICC: 1:250-500; IP: 1:50
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human PI3-K p110 delta was used as an immunogen.
• Formulation: PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• Purification: IgG fraction
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 119 kDa
• Gene Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
• Database Link:
  NP_005017
  Entrez Gene 18707 MouseEntrez Gene 366508 RatEntrez Gene 5293 Human
  UniProt ID O00329
• Background: Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. See MIM 602838. The class I PI3Ks display a broad phosphoinositide lipid substrate specificity and include p110-alpha (MIM 171834), p110-beta (MIM 602925), and p110-gamma (MIM 601232). p110-alpha and p110-beta interact with SH2/SH3-domain-containing p85 adaptor proteins (see MIM 171833) and with GTP-bound Ras. [supplied by OMIM]
• Synonyms: APDS; IMD14; p110D; P110DELTA; PI3K
• Note: Does not react with Mouse, Rat

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Acute myeloid leukemia, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Glioma, Inositol phosphate metabolism, Insulin signaling pathway, Jak-STAT signaling pathway, Leukocyte transendothelial migration, Melanoma, mTOR signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway