MAPKAP Kinase 2 (MAPKAPK2) Rabbit Monoclonal Antibody [Clone ID: E341]

CAT#: TA303762

Rabbit monoclonal antibody against MAPKAP Kinase-2 (E341)

Product Images

Western blot - MAPKAP Kinase 2 antibody [E341]; Anti-MAPKAP Kinase 2 antibody [E341] at 1/1000 dilution + Hela cell lysate.Predicted band size : 46 kDa.Observed band size : 46 kDa.

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  Western blot - Anti-MAPKAP Kinase 2 antibody; Lanes 1 - 2 : Anti-MAPKAP Kinase 2 (phospho T334) antibodyat 1:500.Lanes 3 - 4 : Anti-MAPKAP Kinase 2 antibodyat 1:500.Lane 1 : UV treated HeLa cells.Lane 2 : UV treated HeLa cells + p38 inhibitor.Lane 3 : UV treated HeLa cells.Lane 4 : UV treated HeLa cells + p38 inhibitor.Secondary.IRDye 680 LICOR goat anti-rabbit.Performed under reducing conditions.

Specifications

Product Data

• Clone Name: E341
• Applications: WB
• Recommended Dilution: WB: 1:500-1,000; IP: 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to residues near C-terminus of human MAPKKAP Kinase-2 was used as immunogen.
• Formulation: PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• Purification: IgG fraction
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 46 kDa
• Gene Name: mitogen-activated protein kinase-activated protein kinase 2
• Database Link:
  NP_004750
  Entrez Gene 17164 MouseEntrez Gene 289014 RatEntrez Gene 9261 Human
  UniProt ID P49137
• Background: This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: MAPKAP-K2; MK-2; MK2

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: MAPK signaling pathway, Neurotrophin signaling pathway, VEGF signaling pathway