Tuberin (TSC2) Rabbit Monoclonal Antibody [Clone ID: EP1062Y]

CAT#: TA303844

Rabbit monoclonal antibody against Phospho Tuberin (pS939)(EP1062Y) (Phospho-Specific)

Product Images

Western blot - Tuberin (phospho S939) antibody [EP1062Y]; All lanes : Anti-Tuberin (phospho S939) antibody [EP1062Y] at 1/10000 dilution.Lane 1 : 3T3 cell lysate untreated.Lane 2 : 3T3 cell lysate treated with insulin.Lysates/proteins at 10 ug per lane.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 201 kDa.Observed band size : 180 kDa.

Specifications

Product Data

• Clone Name: EP1062Y
• Applications: WB
• Recommended Dilution: WB: 1:10000; ICC: 1:50 - 1:100
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to residues of human Tuberin was used as an immunogen
• Formulation: PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• Purification: Tissue culture supernatant
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 201 kDa
• Gene Name: tuberous sclerosis 2
• Database Link:
  NP_000539
  Entrez Gene 22084 MouseEntrez Gene 24855 RatEntrez Gene 7249 Human
  UniProt ID P49815
• Background: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
• Synonyms: LAM; PPP1R160; TSC4
• Note: Is unsuitable for Flow Cyt,IHC-Fr,IHC-P or IP.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Insulin signaling pathway, mTOR signaling pathway, p53 signaling pathway