RNF34 Goat Polyclonal Antibody
Other products for "RNF34"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 4-8ug/ml. |
Reactivities | Human |
Host | Goat |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Peptide with sequence KAGATSMWASCC, from the N Terminus of the protein sequence according to NP_919247.1; NP_079402.2. |
Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Concentration | lot specific |
Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | ring finger protein 34 |
Database Link | |
Background | The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq] |
Synonyms | CARP-1; CARP1; hRFI; RFI; RIF; RIFF |
Reference Data | |
Protein Families | Druggable Genome |
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