Heme oxygenase 2 (HMOX2) Goat Polyclonal Antibody

CAT#: TA305779

Goat Anti-HMOX2 Antibody

Product Images

TA305779 (0.3ug/ml) staining of K562 cell lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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  TA305779 (2ug/ml) staining of paraffin embedded Human Pancreas: cancer (left), adjacent to cancer (right). Steamed antigen retrieval with citrate buffer pH 6, Alexa594-staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 0.3-1ug/ml, IHC: 2-4ug/ml
• Reactivities: Human
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-DQAGSTLARETLED, from the internal region of the protein sequence according to NP_002125.3.
• Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: heme oxygenase 2
• Database Link:
  NP_001120676
  Entrez Gene 15369 MouseEntrez Gene 3163 Human
  UniProt ID P30519
• Background: Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus. [provided by RefSeq]
• Synonyms: HO-2

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Porphyrin and chlorophyll metabolism