DNA Ligase I (LIG1) Goat Polyclonal Antibody
Other products for "LIG1"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 0.1-0.3ug/ml. |
Reactivities | Human |
Host | Goat |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Peptide with sequence C-RVREDKQPEQATTS, from the internal region (near C-Terminus) of the protein sequence according to NP_000225.1. |
Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Concentration | lot specific |
Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | DNA ligase 1 |
Database Link | |
Background | LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. [provided by RefSeq] |
Synonyms | MGC117397; MGC130025 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Base excision repair, DNA replication, Mismatch repair, Nucleotide excision repair |
Documents
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