DRAK1 (STK17A) Rabbit Polyclonal Antibody

CAT#: TA306006

Rabbit Polyclonal DRAK1 Antibody

Product Images

Western blot analysis of DRAK1 in (A) MOLT4 and (B) A431 whole cell lysates with DRAK1 antibody at 1 ug/mL.

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  Immunocytochemistry staining of MOLT4 cells using DRAK1 antibody at 2 ug/mL.

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  Immunofluorescence of DRAK1 in Molt cells with DRAK1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 2 ug/mL, IF: 10 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: DRAK1 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human DRAK1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: serine/threonine kinase 17a
• Database Link:
  NP_004751
  Entrez Gene 9263 Human
  UniProt ID Q9UEE5
• Background: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases (1). DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues (1).
• Synonyms: DRAK1

Reference Data

• Protein Families: Druggable Genome, Protein Kinase