TCCR (IL27RA) Rabbit Polyclonal Antibody

CAT#: TA306081

Rabbit Polyclonal TCCR Antibody


USD 430.00

5 Days*

Size
    • 100 ug

Product Images

Other products for "IL27RA"

Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen TCCR antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human TCCR precursor This sequence is identical to that of mouse TCCR.
Formulation PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification Affinity chromatography purified via peptide column
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name interleukin 27 receptor subunit alpha
Background Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned (1,2). It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1 (1,2). TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a . TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.
Synonyms CRL1; IL-27RA; IL27R; TCCR; WSX1; zcytor1
Reference Data
Protein Families Druggable Genome, Transmembrane

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.