DDX3 (DDX3X) Rabbit Polyclonal Antibody

CAT#: TA306299

Rabbit Polyclonal DDX3 Antibody


USD 430.00

5 Days*

Size
    • 100 ug

Product Images

Other products for "DDX3X"

Specifications

Product Data
Applications IF, WB
Recommended Dilution WB: 0.5 - 1 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen DDX3 antibody was raised against a 16 amino acid peptide from near the amino terminus of human DDX3.
Formulation PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification Affinity chromatography purified via peptide column
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name DEAD-box helicase 3, X-linked
Background DDX3 contains all of the motifs of the DEAD-box family of RNA helicases, including the Asp-Glu-Ala-Asp sequence that gives the protein family its name and distinguishes it from other RNA helicases (1,2). DDX3 is localized to the X chromosome and has a highly conserved functional homolog (DBY) on the Y chromosome (3). DDX3 is thought to be involved in RNA splicing, RNA transport, and translation initiation (4). It has also been shown to be involved in cell growth control and is deregulated in hepatitis virus-associated hepatocellular carcinoma (5). Recent experiments suppressing DDX3 expression blocked HIV-1 RNA export from the nucleus, suggesting that DDX3 functions as a shuttling protein that transports the HIV-1 protein Rev and its cofactor CRM1 from the nucleus to the cytoplasm (6).
Synonyms CAP-Rf; DBX; DDX3; DDX14; HLP2
Reference Data
Protein Families ES Cell Differentiation/IPS
Protein Pathways RIG-I-like receptor signaling pathway

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.