Kinesin 5A (KIF5A) Rabbit Polyclonal Antibody

CAT#: TA306456

Rabbit Polyclonal KIF5 Antibody

Product Images

Western blot analysis of KIF5 in K562 cell lysate with KIF5 antibody at (A) 0.5 and (B) 1ug/ml.

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  Immunohistochemistry of KIF5 in mouse brain tissue with KIF5 antibody at 5ug/ml.

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  Immunofluorescence of KIF5 in K562 cells with KIF5 antibody at 20ug/ml.

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  Immunofluorescence of KIF5 in mouse brain tissue with KIF5 antibody at 20ug/ml.

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  Immunocytochemistry of KIF5 in K562 cells with KIF5 antibody at 5ug/ml.

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Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: KIF5 antibody was raised against a 20 amino acid synthetic peptide from near the carboxy terminus of human KIF5. The immunogen is located within amino acids 880 - 930 of KIF5.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: kinesin family member 5A
• Database Link:
  NP_004975
  Entrez Gene 16572 MouseEntrez Gene 314906 RatEntrez Gene 3798 Human
  UniProt ID Q12840
• Background: The kinesin superfamily proteins (KIFs) are microtubule-dependent motors that slide along microtubules and transport cellular organelles and mRNA to different parts of the cell. In neurons, KIF5 performs this role in an anterograde fashion from the neuronal cell body to axonal or dendritic terminals. KIF5 was initially differentiated from the ubiquitously expressed kinesin as being highly enriched in subsets of neurons and selectively concentrated in the cell body. KIF5 has at least three known isoforms; this antibody recognizes all three. Mutations in one of the isoforms of KIF5 (KIF5A) are thought to be involved in hereditary spastic paraplegias.
• Synonyms: D12S1889; MY050; NKHC; SPG10

Reference Data

• Protein Families: Druggable Genome