CCK4 (PTK7) Rabbit Polyclonal Antibody

CAT#: TA306460

Rabbit Polyclonal PTK7 Antibody

Product Images

Western blot analysis of PTK7 in (A) human colon, (B) mouse kidney and (C) rat liver tissue lysate with PTK7 antibody at 1 ug/ml.

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  Immunohistochemistry of PTK7 in human colon tissue with PTK7 antibody at 2.5 ug/ml.

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  Immunofluorescence of PTK7 in Human Colon cells with PTK7 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: PTK7 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human PTK7.
• Formulation: PBS containing 0.02% sodium azide.
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: protein tyrosine kinase 7 (inactive)
• Database Link:
  NP_002812
  Entrez Gene 71461 MouseEntrez Gene 301242 RatEntrez Gene 5754 Human
  UniProt ID Q13308
• Background: Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.
• Synonyms: CCK-4; CCK4

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane