STEAP4 Rabbit Polyclonal Antibody

CAT#: TA306466

Rabbit Polyclonal STEAP4 Antibody

Product Images

Western blot analysis of STEAP4 in rat liver tissue lysate with STEAP4 antibody at (A) 0.5 and (B) 1 ug/ml.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: STEAP4 antibody was raised against a 14 amino acid peptide from near the center of human STEAP4.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: STEAP4 metalloreductase
• Database Link:
  NP_078912
  Entrez Gene 117167 MouseEntrez Gene 499991 RatEntrez Gene 79689 Human
  UniProt ID Q687X5
• Background: The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression. At least two isoforms are known to exist for this protein. This STEAP4 antibody does not cross-react with other STEAP proteins.
• Synonyms: STAMP2; TIARP; TNFAIP9

Reference Data

• Protein Families: Druggable Genome, Transmembrane