METTL7A Rabbit Polyclonal Antibody

CAT#: TA306679

Rabbit Polyclonal MettL7A Antibody

Product Images

Western blot analysis of MettL7A in MCF cell lysate with MettL7A antibody at 2 ug/mL.

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  Immunocytochemistry of MettL7a in MCF7 cells with MettL7a antibody at 2 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 2 ug/mL, ICC: 2 ug/mL, IF: 2 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: MettL7A antibody was raised against a 13 amino acid peptide near the center of human MettL7A.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: methyltransferase like 7A
• Database Link:
  NP_054752
  Entrez Gene 25840 Human
  UniProt ID Q9H8H3
• Background: MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. At least two isoforms of MettL7A are known to exisit. This antibody is predicted to not cross-react with MettL7B.
• Synonyms: AAM-B

Reference Data

• Protein Families: Druggable Genome, Transmembrane